• Senior Scientist Protein Expression and Molecular Biology Jobs in United States Of America - 23783925

  • Pfizer Inc.
  • United States Of America, Usa
  • Save Job
  • 10 - 13 Years
  • Posted : above 1 month

Job Description:

BioMedicine Design (BMD) is seeking a highly motivated scientist to be part of the protein expression and molecular biology group supporting the Biotherapeutics portfolio of Pfizer, Inc in La Jolla, CA The candidate will be responsible for protein expression and DNA construct generation to support the generation of milligram to gram scale quantities of recombinant proteins Constructs will include biotherapeutic leads, protein reagents, recombinant targets, immunogens, and phage/yeast display reagents This position requires strong expertise either in cutting-edge mammalian tissue culture techniques using various cell lines and cell culture technologies and/or the molecular biology aspects of the design, generation, and sequence confirmation of protein expression DNA constructs The ideal candidate will be highly proficient in the design of optimal processes that are consistent with team material needs for quantity and purity

Responsible for the protein expression and molecular-related deliverables of the La Jolla BioMedicines Design protein production group
Perform protein expression in mammalian transient and stable expression cell lines, from various shake flask scales to bioreactor systems
Perform and/or coordinate the generation of DNA constructs tailored for the expression of recombinant proteins
Design, assess and troubleshoot cell culture and expression protocols
Periodically assess site practices and promote the evaluation of new methods and technologies for protein expression and construct generation to optimize delivery to project teams
Deliver DNA constructs, cell culture supernatants and data analysis packages to project teams in a timely manner
Present results regularly at team meetings
Perform diligent and timely notekeeping and work process tracking

Required Qualifications

PhD in molecular biology/biochemistry/immunology/cell biology or a related discipline, 2 years of postdoctoral experience, OR
MS with 7 years biotechnology/pharma experience, or BS with 10 years of biotechnology/pharma experience
Detailed understanding of the scientific and technological principles behind state-of-the-art protein expression systems
Good understanding of the broader biotherapeutics drug discovery process
Extensive experience in protein expression using transient and/or stable mammalian cell culture systems, and strong expertise in design, execution, and troubleshooting of expression processes, AND/OR Extensive expertise in molecular biology techniques, including primer design, PCR, mutagenesis and subcloning techniques, and E coli cell culture
Experience with data analysis and presentation software
Excellent written and oral communication skills

Preferred Qualifications

Experience with Insect Cell expression systems would be highly desirable

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations These laws and regulations require Pfizer to provide government agencies with information such as a health care providers name, address and the type of payments or other value received, generally for public disclosure Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA Pfizer is an E-Verify employer

Other Job Details

Eligible for Relocation Package

*Eligible for Employee Referral Bonus

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates

#LI-PFE

N (Other) (United States of America)

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates

Profile Summary:

Employment Type : Full Time
Eligibility : Any Graduate
Industry : Biotechnology/Pharmaceutical/Medicine, Manufacturing/Industrial
Functional Area : Bio Tech/R&D/Scientist
Role : Bio-Technology Research
Salary : As per Industry Standards
Deadline : 08th Apr 2020

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