• Senior Associate Scientist Jobs in United States Of America

  • Pfizer Inc.
  • United States Of America, Usa
  • Save Job
  • 3 - 6 Years
  • Posted : above 1 month

Job Description:


Cancer Vaccines and Immunotherapeutics seeks to discover novel vaccines for the prevention and treatment of various cancers by using a variety of vaccine technology platforms in combination with immunomodulatory agents We are searching for a motivated individual with practical experience in the implementation of fit for purpose murine tumor models and a scientific understanding of tumor biology and tumor immunology The candidate will be required to proactively apply their knowledge and experience to execute in vivo experimental work plans provided by their supervisor and effectively conduct their work semi-independently and as a member of the ImmunoPharmacology team The candidate will be required to summarize and critique their results, with guidance from their supervisor, as well as on occasion communicate data effectively at work-group meetings This role is laboratory based with a major emphasis placed upon executing murine tumor models The primary role is to assist in the execution of murine tumor models that are designed to understand/refine the mechanism of action responsible for the preclinical efficacy of cancer vaccines and similar immunotherapeutic approaches


Tumor Biology Research

With direction, assist other team members in conducting murine tumor models that measure the preclinical efficacy of cancer vaccines and similar immunotherapeutic approaches

Primary Responsibilities Vivarium/Laboratory and related work (~90 of time) with supervision

Assist in the design and execution of studies of in vivo immuno-oncology-related models in a vivarium

Perform routine animals handling, multi route dosing, tumor measurements, bleeding and terminal procedures

Collect and process tissues and blood for ex vivo analysis

Identify and report any experimental problems, troubleshoot causative factors, and suggest necessary corrections in discussion with supervisor

Support general laboratory operations including ordering and re-stocking laboratory supplies, maintaining a clean and safe work environment and maintenance of equipment

Regularly records experimental work upon completion in electronic notebook systems and archives instrument raw data on server databases

Scientific/ Technical Knowledge

Demonstrated experience in murine tumor models with a basic scientific understanding of tumor biology and tumor immunology

Common laboratory practices such as making solutions and buffers, dilution and other calculations, etc


Communicates effectively with ImmunoPharmacology team members

Actively contributes ideas in group and line meetings

Provides clear, concise and timely responses for data and experimental information to line manager


BS degree in life sciences
3 years of experience working in a laboratory setting that routinely performs in vivo murine experiments
Practical understanding and application of statistical methods to experimental design and outcome measures
Good oral and written communication skills
Effective in communication skills both verbal and written; listens and understands well Excellent interactive skills with people with diverse backgrounds and perspectives
Proactively recognizes needs and problems, and independently identifies and implements effective steps and solutions


Preference for local candidates (no relocation assistance)


Standing, sitting, bending, lifting, walking in a laboratory or vivarium setting

Use of Personal Protective Equipment (PPE) in a BSL-2 laboratory; additional PPE requirements when working in vivarium barrier suites

Standard business office conditions; sitting, standing as appropriate


Lifting, sitting, standing, walking, bending, repetitive pipetting, ability to perform mathematical calculations, ability to read, understand, and perform written protocols, and ability to perform moderately complex data analysis using Microsoft Excel, GraphPad Prism or other similar data analysis software

Routine off-hour and weekend schedule


Adherence to La Jolla EHS policies and training; ability to work with human, non-human primate or murine blood samples and organ tissues
Will be required to work with BSL2 infectious viruses (eg Vaccinia virus, adenovirus, and influenza) and must receive and maintain required vaccinations or provide satisfactory proof of same

Profile Summary:

Employment Type : Full Time
Eligibility : Any Graduate
Industry : Biotechnology/Pharmaceutical/Medicine, Manufacturing/Industrial
Functional Area : HR/PM/IR/Training
Role : Recruitment
Salary : As per Industry Standards
Deadline : 18th Mar 2020

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