• United States Of America, Usa

Job Description:

If youre inspired by the possibilities of science to change lives and you thrive when making brave decisions join us

MedImmune is the worldwide biologics research and development arm of AstraZeneca Here, youll have the opportunity to make a difference in peoples lives every day As one of the worlds premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease Here at MedImmune, youll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients lives

Were constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it Were pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines And were industry-leading in immunology, protein engineering and translational science We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules

MedImmune has a dynamic environment that fosters collaboration and innovation We attract top minds, and we nurture and build top talent

Key Responsibilities

In this role, the Scientist I will be responsible to develop and implement various mass spec-based methods for protein sequence confirmation, identification and quantification of product variants to support process development, product characterization and comparability evaluations Provide high quality data to support the characterization of biopharmaceuticals, such as monoclonal antibodies and recombinant proteins, and aid in drafting of CMC documents for regulatory submissions Actively participate in the activities of cross-functional teams Familiarize with SOP, GLP and GMP requirements during biopharmaceutical product development

Support post-IND characterization using various mass spec-based approaches, including peptide mapping, disulfide bond mapping, intact mass analysis, HDX MS, N-/O-linked glycosylation profiling, de novo sequencing and PTM identification
Operate and maintain mass spec instruments
Keep accurate records of all experiments, data, equipment logs and troubleshoot the instruments as necessary
Make detailed observations, analyze data and interpret data
Present and discuss experimental results at group/project team meetings
Authorize SOPs and other technical documents

Basic Qualifications

Scientist I

PhD degree in analytical science, chemistry, biochemistry or related field (with an emphasis on protein mass spectrometry)

Some related experience post education preferred

5 years of hands-on experience of utilizing LC-MS/MS techniques for protein characterization (can be acquired during PhD study)

Extensive experience on operating and maintaining different mass spec instruments and data analysis software

A strong track record of success

Scientist II

PhD degree in analytical science, chemistry, biochemistry or related field (with an emphasis on protein mass spectrometry)

At least 3 years of industry experience

5 years of hands-on experience of utilizing LC-MS/MS techniques for protein characterization

Extensive experience on operating and maintaining different mass spec instruments and data analysis software

A strong track record of success

Preferred Qualifications

Experience with biopharmaceutical development in the biotech or pharmaceutical industry
In-depth knowledge in separation science and mass spectrometry
Excellent communication skills, both written and verbal
Instinctive team player with excellent people skills
Experience on HDX MS is preferred
Experience on characterization of IgG is a plus

Next Steps Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity If you know someone who would be a great fit, please share this posting with them

AstraZeneca is an equal opportunity employer AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised

Scientist I/II (Mass Spectrometry)

MedImmune

Profile Summary:

Employment Type : Full Time
Eligibility : Any Graduate
Industry : Biotechnology/Pharmaceutical/Medicine, Manufacturing/Industrial
Functional Area : Bio Tech/R&D/Scientist
Role : Bio-Technology Research
Salary : As per Industry Standards
Deadline : 20th Feb 2020

Key Skills:

Company Profile:

Company
ASTRAZENECA PHARMA INDIA LTDarfix

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