• United States Of America, Usa
  • Save Job
  • 8 - 10 Years
  • Posted : above 1 month

Job Description:

AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialisation of prescription medicines for some of the worlds most serious diseases Were proud to have a unique workplace culture that inspires innovation and collaboration We believe in the potential of our people and youll develop beyond what you thought possibleAt AstraZeneca we believe in the potential of our people and youll develop beyond what you thought possible We make the most of your skills and passion by actively supporting you to see what you can achieve We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world If youre curious about what science can do, then youre our kind of person

Main Duties and Responsibilities You will work in the laboratory as member of the expanding Dynamic Omics group using state-of-the-art proteomics technology to investigate a number of biological questions This is a key proteomics application position that requires comprehensive expertise and hands-on experience in this area You must be passionate about life science and lab bench work You must also have a thorough understanding of modern mass spectrometry and chromatography You will support the operation, maintenance and troubleshooting of advanced state-of-the-art nanoflow liquid chromatography and mass spectrometry (LC-MS) instrumentation (Orbitrap Fusion, Agilent IMS-QTOF, QTRAP6500, Q-Exactive HF-X, IDX) that enable cutting-edge proteomic profiling and translational research across our therapeutic areas You have to demonstrate a proven record of being a fast learner, excellent communicator and thoughtful team member

You should be highly motivated, innovative, detail-oriented, creative, well organized and able to work independently when designing and executing experiments and will be expected to manage and prioritize several different projects and tasks in line with the objectives of the group Your projects may include development of novel proteomic technologies or application of already existing ones to address current challenges in biology, and may entail mass spectrometric analysis of cancer cell lines, tissue samples from animal models and patient material

Essential Requirements For AS I - BS in Proteomics, Mass Spectrometry, Analytical Chemistry or related field with 5-8 years of relevant experience, OR MS in Proteomics, Mass Spectrometry, Analytical Chemistry or related field with 3-5 years of relevant experience; for AS II - BS in Proteomics, Mass Spectrometry, Analytical Chemistry or related field with 8-10 years of relevant experience, OR MS in Proteomics, Mass Spectrometry, Analytical Chemistry or related field with 5-8 years of relevant experience

The position is a hands-on, laboratory-based position and should have extensive lab experience in sample preparation
The candidate must have prior experience in nano-liquid chromatography and mass spectrometry (LC-MS; ideally on Orbitrap Fusion, Q-Exactive HF-X, IDX, IMS-QTOF and/or QTRAP)
The candidate must have extensive experience in the operation and troubleshooting of mass spectrometers and is expected to routinely calibrate the instruments
The candidate should be familiar with the entire proteomics pipeline (including sample preparation, LC and MS operation, data analysis) and must be able to conduct independent and creative research
The candidate must demonstrate scientific productivity
The candidate must have excellent oral and written communication skills
An analytical aptitude for devising innovative scientific or technical solutions is highly desired
Furthermore, the candidate should demonstrate enthusiasm, motivation, attention to detail and willingness to learn new technologies, flexibility and confidence

Desirable Requirements Ability to collaborate across multiple disciplines to investigate drug candidates and disease properties

Experience with MaxQuant and Skyline is a strong plus
Ability to publish in peer-reviewed journals, generate technical report summaries and protocols
Cell culture, SDS gel, Western Blot, basic molecular biology skills are a strong plus

Profile Summary:

Employment Type : Full Time
Eligibility : Any Graduate
Industry : Biotechnology/Pharmaceutical/Medicine, Manufacturing/Industrial
Functional Area : Bio Tech/R&D/Scientist
Role : Bio-Technology Research
Salary : As per Industry Standards
Deadline : 06th Apr 2020

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